Chloride Channel, Voltage-Sensitive 7 (CLCN7) (AA 250-300) antibody

Details for Product No. ABIN350221
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Antigen
Synonyms CLC-7, CLC7, OPTA2, OPTB4, PPP1R63, ClC-7
Epitope
AA 250-300
(11), (5), (3), (2), (2)
Reactivity
Human
(21), (12), (10)
Host
Rabbit
(19), (4)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(23), (18), (5), (4), (2), (1)
Pubmed 5 references available
Catalog no. ABIN350221
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from AA 250-300 of human CLCN7 conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TAS2R49 ( and also TAS2R43, TAS2R44, TAS2R46 and TAS2R47. See the Immunogen).
Purification whole serum
Alternative Name Chloride channel protein 7 (CLCN7)
Background Function: Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.
Subcellular location: Lysosome membrane, Multi-pass membrane protein.
Tissue specificity: Brain, testis, muscle and kidney. Also known as: ClC-7, CLCN7, CLC7.
UniProt P59543
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Frattini, Pangrazio, Susani et al.: "Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 18, Issue 10, pp. 1740-7, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16...." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Lam, Tong, Wong et al.: "DNA-based diagnosis of malignant osteopetrosis by whole-genome scan using a single-nucleotide polymorphism microarray: standardization of molecular investigations of genetic diseases due to consanguinity." in: Journal of human genetics, Vol. 52, Issue 1, pp. 98-101, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Hosts (19), (4)
Reactivities (21), (12), (10)
Applications (23), (18), (5), (4), (2), (1)
Epitopes (11), (5), (3), (2), (2)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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