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Details for Product No. ABIN350221

Chloride Channel, Voltage-Sensitive 7 (CLCN7) (Cytoplasmic Domain) antibody

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Antigen
Synonyms CLC-7, CLC7, OPTA2, OPTB4, PPP1R63, ClC-7
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350221
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the cytoplasmic domain of human Chloride channel protein 7 (CLCN7) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for CLCN7.
Purity whole serum
Alternative Name Chloride channel protein 7 (CLCN7)
Background Function: Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.
Subcellular location: Lysosome membrane, Multi-pass membrane protein.
Tissue specificity: Brain, testis, muscle and kidney. Also known as: ClC-7, CLCN7, CLC7.
UniProt P51798
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Frattini, Pangrazio, Susani et al.: "Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 18, Issue 10, pp. 1740-7, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Lam, Tong, Wong et al.: "DNA-based diagnosis of malignant osteopetrosis by whole-genome scan using a single-nucleotide polymorphism microarray: standardization of molecular investigations of genetic diseases due to consanguinity." in: Journal of human genetics, Vol. 52, Issue 1, pp. 98-101, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Alternatives for antigen "Chloride Channel, Voltage-Sensitive 7 (CLCN7)", type "Antibodies"
Hosts (18), (4)
Reactivities (19), (10), (8)
Applications (22), (16), (5), (5), (2), (1), (1)
Epitopes (9), (6), (4), (2), (2)
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