Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350234

Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) (4th Cytoplasmic Loop) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms CNCA, CNCA1, CNG2, OCNC1, OCNCALPHA, OCNCa, Cnca, Cncg4, OLFCH, CNCG2, CNGA2, wu:fj61d07, si:dkey-28h18.1, HCN2
Epitope
»Alternatives 4th Cytoplasmic Loop
Reactivity
»Alternatives Mouse (Murine), Human, Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350234
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 4th cytoplasmic loop of rat CNGA2 (Cyclic nucleotide gated olfactory channel, CNG channel alpha 2) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for AMPA 3.
Purity whole serum
Alternative Name CNGA2
Background Function: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. Theolfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization ofolfactory sensory neurons. Subunit structure: Heterooligomer of OCNC1 and OCNC2 subunits.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity:olfactory neurons. Also known as: Cyclic nucleotide-gatedolfactory channel, Cyclic nucleotide-gated cation channel 2, CNG channel alpha-2, CNG-2, CNG2, CNCA, CNCA1, CNCG2.
UniProt P19492
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Dhallan, Yau, Schrader et al.: "Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons." in: Nature, Vol. 347, Issue 6289, pp. 184-7, 1990 (PubMed).

Distler, Biel, Flockerzi et al.: "Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells." in: Neuropharmacology, Vol. 33, Issue 11, pp. 1275-82, 1995 (PubMed).

Ruiz, London, Nadal-Ginard: "Cloning and characterization of an olfactory cyclic nucleotide-gated channel expressed in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 28, Issue 7, pp. 1453-61, 1996 (PubMed).

Strijbos, Pratt, Khan et al.: "Molecular characterization and in situ localization of a full-length cyclic nucleotide-gated channel in rat brain." in: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4463-7, 2000 (PubMed).

Sjöblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

Alternatives for antigen "Cyclic Nucleotide Gated Channel alpha 2 (CNGA2)", type "Antibodies"
Hosts (29)
Reactivities (25), (19), (18), (12), (12), (12)
Applications (15), (10), (10), (6), (5), (4), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (2), (2), (1), (1), (1), (1)
Beacon