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Beclin 1 antibody (Beclin 1, Autophagy Related) (AA 350-400)

Details for Product anti-BECN1 Antibody No. ABIN350241, Supplier: Login to see
Antigen
  • beclin-1
  • atg6
  • vps30
  • beclin1
  • Beclin-1
  • becn1
  • zgc:73097
  • ATG6
  • VPS30
  • 4921513J16Rik
  • 5430417M23Rik
  • Atg6
Epitope
AA 350-400
34
31
19
14
13
13
13
11
11
9
8
8
8
6
6
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Fruit Fly (Drosophila melanogaster)
353
99
83
13
12
11
10
5
5
3
2
1
1
Host
Rabbit
281
74
4
Clonality
Polyclonal
Conjugate
This Beclin 1 antibody is un-conjugated
20
19
19
19
18
18
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
279
152
119
60
56
48
27
14
14
11
6
2
1
1
Supplier
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Immunogen A synthetic peptide from aa region 350-400 of drosophila Beclin 1 conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for Beclin-1.
Purification Whole serum
Alternative Name Beclin 1 (BECN1 Antibody Abstract)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role inautophagy.
Subcellular location: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein.
Tissue specificity: Ubiquitous Also known as: Beclin-1, BECN1, ATG6, beclin1.
Research Area Cancer, Transcription Factors, Autophagy
Pathways
Application Notes Use at a dilution of 1 : 300 to 1 : 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Adams, Celniker, Holt et al.: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).