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Details for Product No. ABIN350241

Beclin 1, Autophagy Related (BECN1) (C-Term) antibody

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Antigen
Synonyms ATG6, VPS30, beclin1, 4921513J16Rik, 5430417M23Rik, Atg6, zgc:73097, beclin-1, atg6, vps30, Beclin-1, becn1
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN350241
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from c-terminal region of mouse Aquaporin 7 (AQP7) conjugated to an immunogenic carrier protein was used as the antigen.
Isotype IgG
Specificity Specific for Sortilin.
Purity whole serum
Alternative Name coiled-coil myosin-like BCL2-interacting protein (Beclin-1, BECN1, ATG6)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role inautophagy.
Subcellular location: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein.
Tissue specificity: Ubiquitous Also known as: Beclin-1, BECN1, ATG6, beclin1.
UniProt Q99523
Research Area Neurology, Alzheimer's Disease
Application Notes Use at a dilution of 1 : 300 to 1 : 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Adams, Celniker, Holt et al.: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).

Alternatives for antigen "Beclin 1, Autophagy Related (BECN1)", type "Antibodies"
Hosts (134), (62), (2), (1)
Reactivities (175), (90), (55), (47), (34), (23), (20), (15), (12), (8), (2), (1)
Applications (186), (76), (50), (44), (44), (23), (20), (20), (10), (8), (4), (2), (1)
Conjugates (10), (10), (8), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (22), (15), (7), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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