Beclin 1 antibody (Beclin 1, Autophagy Related) (AA 350-400)

Details for Product anti-BECN1 Antibody No. ABIN350241, Supplier: Log in to see
Antigen
  • beclin-1
  • atg6
  • vps30
  • beclin1
  • Beclin-1
  • becn1
  • zgc:73097
  • ATG6
  • VPS30
  • 4921513J16Rik
  • 5430417M23Rik
  • Atg6
  • beclin 1, autophagy related
  • beclin 1
  • beclin 1 protein
  • beclin-1
  • Beclin-1
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)
  • beclin-1-like
  • BECN1
  • becn1
  • atg6
  • CpipJ_CPIJ011087
  • PTRG_07825
  • SJAG_01876
  • Becn1
  • LOC100352353
Alternatives
anti-Human Beclin 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 350-400
32
26
20
16
15
15
13
12
12
12
12
12
10
9
8
8
8
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Fruit Fly (Drosophila melanogaster)
430
154
145
34
23
19
18
14
13
13
8
6
3
3
2
2
1
1
Host
Rabbit
319
117
3
Clonality
Polyclonal
Conjugate
This Beclin 1 antibody is un-conjugated
23
23
23
19
19
19
8
7
7
5
5
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
343
177
161
112
106
72
61
26
26
23
13
6
3
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen A synthetic peptide from aa region 350-400 of drosophila Beclin 1 conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for Beclin-1.
Purification Whole serum
Alternative Name Beclin 1 (BECN1 Antibody Abstract)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role inautophagy.
Subcellular location: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein.
Tissue specificity: Ubiquitous Also known as: Beclin-1, BECN1, ATG6, beclin1.
Research Area Cancer, Transcription Factors, Autophagy
Pathways Autophagy
Application Notes Use at a dilution of 1 : 300 to 1 : 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Adams, Celniker, Holt, Evans, Gocayne, Amanatides, Scherer, Li, Hoskins, Galle, George, Lewis, Richards, Ashburner, Henderson, Sutton, Wortman, Yandell, Zhang, Chen, Brandon, Rogers, Blazej, Champe, Pfeiffer, Wan, Doyle, Baxter, Helt, Nelson, Gabor, Abril: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).

Did you look for something else?