Contactin-3 (BIG-1, CNTN3) (C- or N-Term) antibody

Antigen: Contactin-3 (BIG-1, CNTN3)

Binding Site: C- or N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350246

Additional Information

UniProt: Q9P232

Immunogen: A synthetic peptide from human contactin-3 (contactin 3, BIG-1, PANG, PCS, CNTN3) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION:Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. TISSUE SPECIFICITY: In brain, it is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Also known as: Brain-derived immunoglobulin superfamily protein 1, BIG-1, Plasmacytoma-associated neuronal glycoprotein, PANG,Contactin 3, PCS.

Specificity: Appears to be specific for contactin-3.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Nagase, Kikuno, Ishikawa et al.: "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 2, pp. 143-50, 2000 (PubMed).

Kamei, Takeda, Teramoto et al.: "Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members." in: Genomics, Vol. 69, Issue 1, pp. 113-9, 2000 (PubMed).

Liu, Qian, Gritsenko et al.: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, 2005 (PubMed).

Muzny, Scherer, Kaul et al.: "The DNA sequence, annotation and analysis of human chromosome 3." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).