Contactin 3 (Plasmacytoma Associated) (CNTN3) (N-Term) antibody

Antigen: Contactin 3 (Plasmacytoma Associated) (CNTN3)

Synonyms: PCS, PANG, BIG-1, KIAA1496, Pang

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus), Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350247

Additional Information

Alternative name: Contactin-3 (contactin 3, PANG, PCS, CNTN3)

Swiss-Prot: Q62682

Immunogen: A synthetic peptide as a part of rat, mouse contactin-3 (BIG-1, contactin 3, PANG, PCS, CNTN3) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Neural adhesion molecule; may be involved in maintaining neural networks in the brain. FUNCTION:Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. TISSUE SPECIFICITY: Specifically expressed in brain. Ectopically expressed in tumors expressing endogenous intracisternal A-type particles (IAPs). Also known as: Brain-derived immunoglobulin superfamily protein 1, BIG-1, Plasmacytoma-associated neuronal glycoprotein, PANG,Contactin 3, PCS.

Specificity: Appears to be specific for contactin-3.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Connelly, Grady, Mushinski et al.: "PANG, a gene encoding a neuronal glycoprotein, is ectopically activated by intracisternal A-type particle long terminal repeats in murine plasmacytomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 4, pp. 1337-41, 1994 (PubMed).