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Details for Product No. ABIN350255

Contactin 6 (CNTN6) (C- or N-Term) antibody

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Synonyms NB3, NB-3, DKFZp459A015
»Alternatives C- or N-Term
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN350255
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human contactin-6 (NB3, contactin 6, CNTN6) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for contactin-6.
Purity whole serum
Alternative Name Contactin-6 (NB3,Contactin 6, CNTN6)
Background The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.
Function:Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
Subcellular location: Cell membrane, Lipid-anchor, GPI-anchor.
Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. Also known as: Neural recognition molecule NB-3, NB3,Contactin 6, CNTN6.
UniProt Q9UQ52
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Kamei, Tsutsumi, Taketani et al.: "cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human." in: Journal of neuroscience research, Vol. 51, Issue 3, pp. 275-83, 1998 (PubMed).

Sjöblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

Alternatives for antigen "Contactin 6 (CNTN6)", type "Antibodies"
Hosts (28), (1), (1)
Reactivities (23), (23), (16), (13), (12), (12)
Applications (14), (10), (10), (4), (4), (4), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (7), (1)