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Details for Product No. ABIN350267

C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5) (Internal Region) antibody

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Antigen
Synonyms CTRP5, Ctrp5, C1QTNF5, wu:fb02c10, wu:fb02f05, zgc:112378
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine)
Host
»Alternatives Sheep
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350267
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from internal region of human CTRP5 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Specificity Specific for SYTI.
Purity whole serum
Alternative Name CTRP5 (Complement C1q tumor necrosis factor-related protein 5, C1QTNF5)
Background Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). LORD is an autosomal dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal neovascularization and chorioretinal atrophy.
Subcellular location: Secreted Also known as: Complement C1q tumor necrosis factor-related protein 5, C1QTNF5.
UniProt P46096
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Hayward, Shu, Cideciyan et al.: "Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2657-67, 2003 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Zhang, Henzel: "Signal peptide prediction based on analysis of experimentally verified cleavage sites." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2819-24, 2004 (PubMed).

Taylor, Noguchi, Totoki et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006 (PubMed).

Alternatives for antigen "C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5)", type "Antibodies"
Hosts (54), (2), (2), (1)
Reactivities (58), (24), (16), (12), (12), (12)
Applications (50), (23), (15), (10), (7), (3), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (12), (6), (5), (2), (1), (1)
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