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Details for Product No. ABIN350298

Dynamin 1 (Dynamin-1, B-Dynamin, Dynamin, Dnm1) (C-Term) antibody

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Antigen
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350298
Quantity 150 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of rat Dynamin 1 (Dynamin-1, B-dynamin, Dynamin, Dnm1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in human and mouse.
Specificity Appears to be specific for Dynamin 1.
Purity whole serum
Background Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.
Catalytic activity: GTP + H(2)O = GDP + phosphate.
Subcellular location: Cytoplasm. Cytoplasm › cytoskeleton. Also known as: Dynamin-1, D100, DNM, EC 3.6.5.5, B dynamin, DNM 1, DNM1, Dynamin, Dynamin BREDNM19, Dynamin1.
UniProt P21575
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Obar, Collins, Hammarback et al.: "Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins." in: Nature, Vol. 347, Issue 6290, pp. 256-61, 1990 (PubMed).

Ringstad, Nemoto, De Camilli: "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 16, pp. 8569-74, 1997 (PubMed).

Cousin, Robinson: "The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis." in: Trends in neurosciences, Vol. 24, Issue 11, pp. 659-65, 2001 (PubMed).

Reubold, Eschenburg, Becker et al.: "Crystal structure of the GTPase domain of rat dynamin 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13093-8, 2005 (PubMed).

Graham, Anggono, Bache et al.: "The in vivo phosphorylation sites of rat brain dynamin I." in: The Journal of biological chemistry, Vol. 282, Issue 20, pp. 14695-707, 2007 (PubMed).

Alternatives for antigen "Dynamin 1 (Dynamin-1, B-Dynamin, Dynamin, Dnm1)", type "Antibodies"
Hosts (1)
Reactivities (1), (1), (1)
Applications (1), (1)
Epitopes (1)
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