Dynamin 1 (Dynamin-1, B-Dynamin, Dynamin, Dnm1) (C-Term) antibody

Details for Product No. ABIN350298
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Human, Mouse (Murine), Rat (Rattus)
(1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(1), (1)
Pubmed 5 references available
Catalog no. ABIN350298
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 7 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the c-terminal region of rat Dynamin 1 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in human and mouse.
Isotype IgG
Specificity Specific for CACNG8.
Purification whole serum
Background Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.
Catalytic activity: GTP + H(2)O = GDP + phosphate.
Subcellular location: Cytoplasm. Cytoplasm › cytoskeleton. Also known as: Dynamin-1, D100, DNM, EC, B dynamin, DNM 1, DNM1, Dynamin, Dynamin BREDNM19, Dynamin1.
UniProt Q8VHW5
Research Area Signaling
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Obar, Collins, Hammarback et al.: "Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins." in: Nature, Vol. 347, Issue 6290, pp. 256-61, 1990 (PubMed).

Ringstad, Nemoto, De Camilli: "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 16, pp. 8569-74, 1997 (PubMed).

Cousin, Robinson: "The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis." in: Trends in neurosciences, Vol. 24, Issue 11, pp. 659-65, 2001 (PubMed).

Reubold, Eschenburg, Becker et al.: "Crystal structure of the GTPase domain of rat dynamin 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13093-8, 2005 (PubMed).

Graham, Anggono, Bache et al.: "The in vivo phosphorylation sites of rat brain dynamin I." in: The Journal of biological chemistry, Vol. 282, Issue 20, pp. 14695-707, 2007 (PubMed).

Hosts (1)
Reactivities (1), (1)
Applications (1), (1)
back to top