SLC1A3 antibody (C-Term)

Catalog No. ABIN350311

Product Details anti-SLC1A3 Antibody

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Binding Specificity: C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for EAAT1.

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from c-terminal region of mouse EAAT1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SLC1A3

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Alternative Name: SLC1A3 (SLC1A3 Products)

Synonyms: AF001784 antibody, CG3747 antibody, Dglt-1 antibody, Dglut-1 antibody, Dmel\\CG3747 antibody, EAAT antibody, EAAT1 antibody, dEAAT antibody, dEAAT1 antibody, dEaat1 antibody, slc1a3 antibody, wu:fb98e05 antibody, wu:fd50b05 antibody, zgc:56661 antibody, zgc:77768 antibody, SLC1A3 antibody, GLAST antibody, GluT-1 antibody, EA6 antibody, GLAST1 antibody, AI504299 antibody, B430115D02Rik antibody, Eaat1 antibody, GLAST-1 antibody, GLU-T antibody, Gmt1 antibody, MGluT1 antibody, Excitatory amino acid transporter 1 antibody, solute carrier family 1 member 3 antibody, excitatory amino acid transporter 1 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 3a antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 3 antibody, Eaat1 antibody, SLC1A3 antibody, PTRG_00379 antibody, Tsp_02392 antibody, slc1a3a antibody, Slc1a3 antibody

Background: FUNCTION: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Defects in SLC1A3 are the cause of episodic ataxia type 6 (EA6). EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.,SLC1 Family,Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3, SLC1A3, EAAT1, GLAST, GLAST1

UniProt: P56564

Pathways: Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport