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Details for Product No. ABIN350333

GBB3 (Transducin beta Chain 3, GNB3, Guanine Nucleotide Binding Protein Subunit beta-3) (N-Term) antibody

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Antigen
Epitope
N-Term
Reactivity
Human, Mouse (Murine), Rat (Rattus)
Host
Rabbit
Clonality Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350333
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the n-terminal of human GBB3 (Transducin beta chain 3, GNB3, Guanine nucleotide binding protein subunit beta-3) conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in rat and mouse.
Specificity Appears to be specific for GBB3.
Purity whole serum
Background Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in varioustransmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Also known as: Transducin beta chain 3, GNB3, Guanine nucleotide binding protein subunit beta-3.
UniProt P16520
Application Notes IHC, WB. A dilution of 1: 300 to 1: 5000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Levine, Smallwood, Moen et al.: "Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 6, pp. 2329-33, 1990 (PubMed).

Ansari-Lari, Muzny, Lu et al.: "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13." in: Genome research, Vol. 6, Issue 4, pp. 314-26, 1996 (PubMed).

Ansari-Lari, Shen, Muzny et al.: "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination." in: Genome research, Vol. 7, Issue 3, pp. 268-80, 1997 (PubMed).

Rosskopf, Busch, Manthey et al.: "G protein beta 3 gene: structure, promoter, and additional polymorphisms." in: Hypertension, Vol. 36, Issue 1, pp. 33-41, 2000 (PubMed).

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