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Histatin 1 (HTN1) (Internal Region) antibody

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Synonyms HIS1
Internal Region
(11), (2), (1)
(9), (7)
(3), (3)
Immunohistochemistry (IHC), Western Blotting (WB)
(10), (9), (3), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from internal region of human Histatin-1 conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for Histatin-1.
Purification Whole serum
Alternative Name Histatin 1 (HTN1 Antibody Abstract)
Background Function: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.
Tissue specificity: Submandibular and parotid glands. Also known as: Histatin-1, Histidine-rich protein 1, HTN1, HIS1.
Research Area Signaling, Extracellular Matrix
Application Notes Use at a dilution of 1:100 to 1: 2000.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Cabras, Fanali, Monteiro et al.: "Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland." in: Journal of proteome research, Vol. 6, Issue 7, pp. 2472-80, 2007 (PubMed).

Oppenheim, Yang, Diamond et al.: "The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion." in: The Journal of biological chemistry, Vol. 261, Issue 3, pp. 1177-82, 1986 (PubMed).

Oppenheim, Xu, McMillian et al.: "Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans." in: The Journal of biological chemistry, Vol. 263, Issue 16, pp. 7472-7, 1988 (PubMed).

vanderSpek, Wyandt, Skare et al.: "Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs." in: American journal of human genetics, Vol. 45, Issue 3, pp. 381-7, 1989 (PubMed).

Sugiyama, Ogino, Ogata: "Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva." in: Archives of oral biology, Vol. 35, Issue 6, pp. 415-9, 1990 (PubMed).

Catalog No. ABIN350373
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