»
Antibodies
»
anti-Homer Homolog 3 (Drosophila) (HOMER3) (internal) antibody
Homer Homolog 3 (Drosophila) (HOMER3) (internal) antibody
| Antigen |
|
| Synonyms |
Vesl-3, HOMER3, MGC55557, VESL3, HOMER-3, AW146114 |
|
Epitope
|
|
| Clonality |
Polyclonal |
|
Host
|
|
|
Application
|
 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Flow Cytometry (FACS) (19), Immunofluorescence (IF) (18), Western Blotting (WB) (8), ELISA (4), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
|
| Catalog no. |
ABIN350375 |
| Quantity |
100 µl |
| Price |
413.33 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Alternative name
|
HOMER3 (Home3, Vesl-3, Vesl3, Homer-3) (internal region)
|
|
Swiss-Prot
|
Q9Z2X5
|
|
Immunogen
|
A synthetic peptide from the internal part of rat HOMER3 (Home3, Vesl-3, Vesl3, Homer-3) conjugated to an immunogenic carrier protein was used as the immunogen.
|
|
Format
|
Lyophilized
|
|
Description
|
FUNCTION: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors it aids the coupling of surface receptors to intracellular calcium release. SUBUNIT: Encodes coiled-coil structures that mediate homo- and heteromultimerization. SUBCELLULAR LOCATION: Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note: Postsynaptic density of neuronal cells. It may interact with group I metabotropic glutamate receptors and regulate their coupling to membrane ion channels. Also known as: Home3, Homer protein homolog 3, VASP/Ena-related gene up-regulated during seizure and LTP 3, Vesl-3, Vesl3.
|
|
Specificity
|
Appears to be specific for Homer3.
|
|
Application Notes
|
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
|
|
Purity
|
whole serum
|
|
Storage
|
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Homer Homolog 3 (Drosophila) (HOMER3)", type "Antibodies"
|
Hosts
|
Rabbit (23), Mouse (2)
|
|
Reactivities
|
Human (25), Mouse (Murine) (19), Dog (Canine) (16), Rat (Rattus) (16), Chicken (15), Cow (Bovine) (15), Horse (Equine) (1), Pig (Porcine) (1)
|
|
Applications
|
Flow Cytometry (FACS) (19), Immunofluorescence (IF) (18), Western Blotting (WB) (8), ELISA (4), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
|
|
Conjugates
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitopes
|
Center (1), pThr36 (1)
|
