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Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) (C-Term) antibody

Details for Product No. ABIN350380
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Antigen
Synonyms ERG, gp-erg, ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1, KCNH2, erg, LQT, Lqt2, M-erg, Merg1, merg1a, merg1b, AI326795, cerg, derg, erg1
Epitope
C-Term
(16), (11), (4), (3), (3), (2), (1), (1), (1)
Reactivity
Human, Rat (Rattus)
(60), (23), (20), (14), (12), (1)
Host
Sheep
(65), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(53), (29), (19), (10), (8), (4), (4), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 100 µL
Options
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Availability Will be delivered in 7 to 8 Business Days
Catalog No. ABIN350380
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the c-terminal region of human KCNH2 (Potassium voltage-gated channel subfamily H member 2, Kv11.1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in mouse and rat.
Specificity Specific for p75NTR.
Purification whole serum
Alternative Name KCNH2 (Potassium voltage-gated channel subfamily H member 2, Kv11.1)
Background Function: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Isoform 1 is expressed in heart, brain and testis and at low levels in lung. Isoform 3 is expressed predominantly in heart. The expression of isoform 2 is low in all tissues tested. Also known as: Potassium voltage-gated channel subfamily H member 2, Voltage-gated potassium channel subunit Kv11.1, Ether-a-go-go-related gene potassium channel 1, H-ERG, Erg1, Ether-a-go-go-related protein 1, Eag-related protein 1, eag homolog, ERG, ERG1, HERG, HERG1.
UniProt P07174
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Lees-Miller, Kondo, Wang et al.: "Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts." in: Circulation research, Vol. 81, Issue 5, pp. 719-26, 1997 (PubMed).

London, Trudeau, Newton et al.: "Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current." in: Circulation research, Vol. 81, Issue 5, pp. 870-8, 1997 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350380
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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