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Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) (C-Term) antibody

Details for Product No. ABIN350381
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Antigen
Synonyms ERG, gp-erg, ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1, KCNH2, erg, LQT, Lqt2, M-erg, Merg1, merg1a, merg1b, AI326795, cerg, derg, erg1
Epitope
C-Term
(16), (11), (4), (3), (3), (2), (1), (1), (1)
Reactivity
Human, Rat (Rattus)
(60), (23), (20), (14), (12), (1)
Host
Rabbit
(64), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(53), (29), (19), (10), (8), (4), (4), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 500 µg
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Catalog No. ABIN350381
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the c-terminal region of human KCNH2 (Potassium voltage-gated channel subfamily H member 2, Kv11.1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for p75NTR.
Purification IgG
Alternative Name KCNH2 (Potassium voltage-gated channel subfamily H member 2, Kv11.1)
Background Function: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Isoform 1 is expressed in heart, brain and testis and at low levels in lung. Isoform 3 is expressed predominantly in heart. The expression of isoform 2 is low in all tissues tested. Also known as: Potassium voltage-gated channel subfamily H member 2, Voltage-gated potassium channel subunit Kv11.1, Ether-a-go-go-related gene potassium channel 1, H-ERG, Erg1, Ether-a-go-go-related protein 1, Eag-related protein 1, eag homolog, ERG, ERG1, HERG, HERG1.
UniProt P07174
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Lees-Miller, Kondo, Wang et al.: "Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts." in: Circulation research, Vol. 81, Issue 5, pp. 719-26, 1997 (PubMed).

London, Trudeau, Newton et al.: "Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current." in: Circulation research, Vol. 81, Issue 5, pp. 870-8, 1997 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350381
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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