KCNJ10 antibody (AA 330-379)

Catalog No. ABIN350385

Product Details anti-KCNJ10 Antibody

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Binding Specificity: AA 330-379

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for KCNJ10.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 330-379 of human KCNJ10 conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Alternative Name: KCNJ10 (KCNJ10 Products)

Synonyms: kir1.2 antibody, kir4.1 antibody, birk-10 antibody, MGC145926 antibody, BIR10 antibody, BIRK-1 antibody, Kir1.2 antibody, Kir4.1 antibody, BIRK-10 antibody, KCNJ13-PEN antibody, KIR1.2 antibody, KIR4.1 antibody, SESAME antibody, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog antibody, potassium voltage-gated channel subfamily J member 10 antibody, potassium channel, inwardly rectifying subfamily J, member 10 antibody, potassium inwardly-rectifying channel, subfamily J, member 10 antibody, kcnj10.L antibody, KCNJ10 antibody, kcnj10 antibody, Kcnj10 antibody

Background: FUNCTION: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Subcellular location: Membrane, Multi-pass membrane protein.,Inward Rectifier,ATP-sensitive inward rectifier potassium channel 10, Potassium channel, inwardly rectifying subfamily J member 10, Inward rectifier K(+) channel Kir1.2, ATP-dependent inwardly rectifying potassium channel Kir4.1

UniProt: P78508

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity