Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15) (Cytoplasmic Domain) antibody

Details for Product No. ABIN350392
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms KCNJ15, IRKK, KIR1.3, KIR4.2, 4930414N08Rik, AI182284, AI267127, Kir4.2, Kir1.3
Epitope
Cytoplasmic Domain
(7), (7), (6), (1), (1), (1)
Reactivity
Human
(21), (3), (3)
Host
Rabbit
(11), (10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(21), (17), (3), (2)
Pubmed 4 references available
Quantity 100 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 7 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350392
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the cytoplasmic domain of human KCNJ15 (KCNJ14, Kir4.2) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for KCNJ15.
Purification Whole serum
Alternative Name KCNJ15
Background Function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: ATP-sensitive inward rectifier potassium channel 15, Potassium channel, inwardly rectifying subfamily J member 15, Inward rectifier K(+) channel Kir4.2, KCNJ14, Kir4.2.
Research Area Signaling, Metabolism
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Shuck, Piser, Bock et al.: "Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3)." in: The Journal of biological chemistry, Vol. 272, Issue 1, pp. 586-93, 1997 (PubMed).

Gosset, Ghezala, Korn et al.: "A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1)." in: Genomics, Vol. 44, Issue 2, pp. 237-41, 1997 (PubMed).

Kurschner, Mermelstein, Holden et al.: "CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins." in: Molecular and cellular neurosciences, Vol. 11, Issue 3, pp. 161-72, 1998 (PubMed).

Sjöblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers. ..." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

Validation Images
Did you look for something else?
back to top