KCNJ8 antibody (Cytoplasmic Domain)

Catalog No. ABIN350401

Product Details anti-KCNJ8 Antibody

Target: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Binding Specificity: Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for KCNJ8.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the cytoplasmic domain of human KCNJ8 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for KCNJ8

Target: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Alternative Name: KCNJ8 (KCNJ8 Products)

Synonyms: kir6.1 antibody, KIR6.1 antibody, uKATP-1 antibody, AI448900 antibody, Kir6.1 antibody, gnite antibody, slmbr antibody, sltr antibody, UKATP1 antibody, si:dkey-183c2.2 antibody, zkir6.1 antibody, potassium voltage-gated channel subfamily J member 8 antibody, potassium channel, inwardly rectifying subfamily J, member 8 antibody, potassium inwardly-rectifying channel, subfamily J, member 8 antibody, potassium channel, inwardly rectifying subfamily J, member 8 S homeolog antibody, KCNJ8 antibody, kcnj8 antibody, Kcnj8 antibody, kcnj8.S antibody

Background: FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. Subcellular location: Membrane, Multi-pass membrane protein.,Inward Rectifier,ATP-sensitive inward rectifier potassium channel 8, Potassium channel, inwardly rectifying subfamily J member 8, Inwardly rectifier K(+) channel Kir6.1, uKATP-1

UniProt: Q15842