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Details for Product No. ABIN350402

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 9 (KCNJ9) (Cytoplasmic Domain) antibody

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Antigen
Synonyms GIRK3, KIR3.3, 1700085N21Rik, Girk3, Kir3.3, mbGIRK3
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN350402
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the cytoplasmic domain of human KCNJ9 (Kir3.3, GIRK3) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.
Specificity Appears to be specific for KCNJ9.
Purity whole serum
Alternative Name KCNJ9 (Kir3.3, GIRK3)
Background Function: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Tissue specificity: Expressed mainly in the brain, some expression in the skeletal muscle.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: G protein-activated inward rectifier potassium channel 3, GIRK3, Potassium channel, inwardly rectifying subfamily J member 9, Inwardly rectifier K(+) channel Kir3.3.
UniProt Q92806
Application Notes IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Schoots, Wilson, Ethier et al.: "Co-expression of human Kir3 subunits can yield channels with different functional properties." in: Cellular signalling, Vol. 11, Issue 12, pp. 871-83, 2000 (PubMed).

Vaughn, Wolford, Prochazka et al.: "Genomic structure and expression of human KCNJ9 (Kir3.3/GIRK3)." in: Biochemical and biophysical research communications, Vol. 274, Issue 2, pp. 302-9, 2000 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).

Alternatives for antigen "Potassium Inwardly-Rectifying Channel, Subfamily J, Member 9 (KCNJ9)", type "Antibodies"
Hosts (33)
Reactivities (30), (30), (28), (17), (17)
Applications (19), (15), (11), (10), (6), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (2), (2), (1), (1)
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