Function: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K+ currents. Inhibited by Ba2+, quinine, quinidine, chloroform and halothane. Activated at alkaline pH.
Tissue specificity: Highly expressed in pancreas. Not detectable in the other tissues tested.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Potassium channel subfamily K member 16, TWIK-related alkaline pH-activated K(+) channel 1, 2P domain potassium channel Talk-1, TALK1.