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Details for Product No. ABIN350415

Potassium Channel Subfamily K Member 6 (KCNK6) (C-Term) antibody

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Antigen
Synonyms K2p6.1, KCNK8, TOSS, TWIK-2, TWIK2, Twik2, Twik-2, im:7152114, zgc:110418
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350415
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of rat KCNK6 (TOSS, TWIK2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for KCNK6.
Purity whole serum
Alternative Name KCNK6 (TOSS, TWIK2)
Background Function: Exhibits outward rectification in a physiological K+ gradient and mild inward rectification in symmetrical K+ conditions. Inhibited by internal acidification and, to a small degree, by zinc. Not inhibited by quinine, quinidine or barium.
Tissue specificity: Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Potassium channel subfamily K member 6, Inward rectifying potassium channel protein TWIK-2, TWIK-originated similarity sequence, TOSS, TWIK2.
UniProt Q9ERU5
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Carninci, Hayashizaki: "High-efficiency full-length cDNA cloning." in: Methods in enzymology, Vol. 303, pp. 19-44, 1999 (PubMed).

Patel, Maingret, Magnone et al.: "TWIK-2, an inactivating 2P domain K+ channel." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 28722-30, 2000 (PubMed).

Shibata, Itoh, Aizawa et al.: "RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." in: Genome research, Vol. 10, Issue 11, pp. 1757-71, 2000 (PubMed).

Kawai, Shinagawa, Shibata et al.: "Functional annotation of a full-length mouse cDNA collection." in: Nature, Vol. 409, Issue 6821, pp. 685-90, 2001 (PubMed).

Okazaki, Furuno, Kasukawa et al.: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." in: Nature, Vol. 420, Issue 6915, pp. 563-73, 2002 (PubMed).

Alternatives for antigen "Potassium Channel Subfamily K Member 6 (KCNK6)", type "Antibodies"
Hosts (9)
Reactivities (8)
Applications (9), (1), (1), (1)
Epitopes (3), (2), (2)
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