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Details for Product No. ABIN350423

KCNN1 (SK, SK1) (C-Term) antibody

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Antigen
Epitope
»Alternatives C-Term
Reactivity
Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN350423
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from c-terminal region of human KCNN1 (SK, SK1) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for KCNN1.
Purity whole serum
Background Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Small conductance calcium-activated potassium channel protein 1, SK1, SK.
UniProt Q92952
Application Notes IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Koehler, Hirschberg, Bond et al.: "Small-conductance, calcium-activated potassium channels from mammalian brain." in: Science (New York, N.Y.), Vol. 273, Issue 5282, pp. 1709-14, 1996 (PubMed).

Joiner, Wang, Tang et al.: "hSK4, a member of a novel subfamily of calcium-activated potassium channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 20, pp. 11013-8, 1997 (PubMed).

Litt, LaMorticella, Bond et al.: "Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1)." in: Cytogenetics and cell genetics, Vol. 86, Issue 1, pp. 70-3, 1999 (PubMed).

Hoffert, Pisitkun, Wang et al.: "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 7159-64, 2006 (PubMed).

Imami, Sugiyama, Kyono et al.: "Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column." in: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, Vol. 24, Issue 1, pp. 161-6, 2008 (PubMed).

Alternatives for antigen "KCNN1 (SK, SK1)", type "Antibodies"
Hosts (1)
Applications (1), (1)
Epitopes (1)
Beacon