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Details for Product No. ABIN350432

LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (C-Term) antibody

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Antigen
Synonyms wts, WARTS, AW208599, RGD1564085, Lats, si:dkey-181i3.5, wu:fc19a11, zgc:123219, lats1
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350432
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide to the c-terminal of mouse LATS1 (WARTS) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for LATS1.
Purity whole serum
Alternative Name LATS1 (WARTS)
Background Function: Tumor suppressor which plays a critical role in maintenance of ploidy through its actions in both mitotic progression and the G1 tetraploidy checkpoint. Involved in the control of p53 expression. Affects cytokinesis by regulating actin polymerization through negative modulation of LIMK1. May also play a role in endocrine function.
Subcellular location: Centrosome, Spindle. Note: Localizes to the centrosomes throughout interphase but migrates to the mitotic apparatus, including spindle pole bodies, mitotic spindle, and midbody, during mitosis. Also known as: Serine/threonine-protein kinase LATS1, Large tumor suppressor homolog 1, WARTS protein kinase.
UniProt Q8BYR2
Application Notes IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Tao, Zhang, Turenchalk et al.: "Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity." in: Nature genetics, Vol. 21, Issue 2, pp. 177-81, 1999 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Di Betta, Mittempergher, Nascimbeni et al.: "Outcome of duodenal switch with a transitory vertical gastroplasty, in super-super-obese patients in an 8-year series." in: Obesity surgery, Vol. 18, Issue 2, pp. 182-6, 2008 (PubMed).

Trost, English, Lemieux et al.: "The phagosomal proteome in interferon-gamma-activated macrophages." in: Immunity, Vol. 30, Issue 1, pp. 143-54, 2009 (PubMed).

Alternatives for antigen "LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)", type "Antibodies"
Hosts (51), (2)
Reactivities (52), (44), (43), (24), (24), (24), (12)
Applications (30), (25), (19), (12), (3), (1), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (14), (12), (4), (2), (1), (1), (1), (1), (1)
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