Mal, T-Cell Differentiation Protein 2 (MAL2) (C-Term) antibody

Antigen: Mal, T-Cell Differentiation Protein 2 (MAL2)

Synonyms: AI461653, MGC130604, MGC80920

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350437

Additional Information

Alternative name: MAL2 (c-terminal region)

Swiss-Prot: Q8BI08

Immunogen: A synthetic peptide from the c-terminal region of mouse MAL2 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.

Format: Lyophilized

Description: FUNCTION: Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note: Associated with lipid rafts. In polarized epithelial cells, restricted to the apical surface. Also known as: Mal2.

Specificity: Appears to be specific for MAL2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Florea, Di Francesco, Miller et al.: "Gene and alternative splicing annotation with AIR." in: Genome research, Vol. 15, Issue 1, pp. 54-66, 2005 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).