You are viewing an incomplete version of our website. Please click to reload the website as full version.

MAP2 antibody (MAP-2)

Details for Product anti-MAP-2 Antibody No. ABIN350438, Supplier: Log in to see
Antigen
  • a730034c02
  • MAP-2
  • MAP2A
  • MAP2B
  • MAP2C
  • MAP2R
  • MGC53131
  • Mtap-2
  • Mtap2
  • p67
  • p67eIF2
  • xmap2
Reactivity
Human
288
176
146
120
26
19
15
13
7
5
3
1
Host
Rabbit
170
169
18
3
Clonality
Polyclonal
Conjugate
This MAP2 antibody is un-conjugated
17
16
12
12
8
8
6
5
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
266
133
115
101
96
64
49
29
23
22
13
13
11
4
3
3
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen A synthetic peptide from human MAP2 conjugated to blue carrier protein was used as the antigen.
Specificity Specific for MAP-2.
Purification Whole serum
Alternative Name MAP2
Background Regulates and organizes microtubules, may serve as a scaffolding protein for neuromodulatory activities.
Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Subcellular location: Cytoplasm, cytoskeleton.
Developmental stage: Isoform MAP2C is expressed during embryonic brain development and until postanatal day 10. Isoform MAP2B is expressed throughout brain development. Also known as: Microtubule-associated protein 2, MAP 2, MAP-2, MAP2R.
Research Area Stem Cells, Cytoskeleton
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Cantin, Yi, Lu, Park, Xu, Lee, Yates: "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis." in: Journal of proteome research, Vol. 7, Issue 3, pp. 1346-51, 2008 (PubMed).

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Sjöblom, Jones, Wood, Parsons, Lin, Barber, Mandelker, Leary, Ptak, Silliman, Szabo, Buckhaults, Farrell, Meeh, Markowitz, Willis, Dawson, Willson, Gazdar, Hartigan, Wu, Liu, Parmigiani, Park et al.: "The consensus coding sequences of human breast and colorectal cancers. ..." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

DeGiorgis, Jaffe, Moreira, Carlotti, Leite, Pant, Dosemeci: "Phosphoproteomic analysis of synaptosomes from human cerebral cortex." in: Journal of proteome research, Vol. 4, Issue 2, pp. 306-15, 2005 (PubMed).

Albala, Kalcheva, Shafit-Zagardo: "Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2)." in: Gene, Vol. 136, Issue 1-2, pp. 377-8, 1994 (PubMed).

Dammerman, Yen, Shafit-Zagardo: "Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles." in: Journal of neuroscience research, Vol. 24, Issue 4, pp. 487-95, 1990 (PubMed).

Kosik, Orecchio, Bakalis, Duffy, Neve: "Partial sequence of MAP2 in the region of a shared epitope with Alzheimer neurofibrillary tangles." in: Journal of neurochemistry, Vol. 51, Issue 2, pp. 587-98, 1988 (PubMed).