Mas-Related G-Protein Coupled Receptor Member E (MRGPRE) (3d cytoplasmic loop) antibody

Antigen: Mas-Related G-Protein Coupled Receptor Member E (MRGPRE)

Synonyms: MrgE

Epitope: 3d cytoplasmic loop

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus), Mouse (Murine)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN350445

Additional Information

Alternative name: Mas-related G-protein coupled receptor member E (MRGPRE) (3d cytoplasmic loop)

Swiss-Prot: Q7TN40

Immunogen: A synthetic peptide from the 3d cytoplasmic loop of rat Mas-related G-protein coupled receptor member E (MRGPRE) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous with the corresponding sequence in mouse.

Format: Lyophilized

Description: FUNCTION: Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Also known as: Mas-related G-protein coupled receptor member E, Mrge, MrgE.

Specificity: Appears to be specific for MRGPRE.

Application Details

Application Notes: IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Milasta, Pediani, Appelbe et al.: "Interactions between the Mas-related receptors MrgD and MrgE alter signalling and trafficking of MrgD." in: Molecular pharmacology, Vol. 69, Issue 2, pp. 479-91, 2006 (PubMed).