Meteorin, Glial Cell Differentiation Regulator (METRN) (internal) antibody

Antigen: Meteorin, Glial Cell Differentiation Regulator (METRN)

Synonyms: MGC2601, C16orf23, c380A1.2, Hyrac, 1810034B16Rik, RGD1306222, mtrn, zgc:92132, wu:fb81a08, METRN

Epitope: internal

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350460

Additional Information

Alternative name: Meteorin (METRN) (internal region)

Swiss-Prot: Q9UJH8

Immunogen: A synthetic peptide from the internal region of human Meteorin (METRN) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Subcellular location: Secreted Also known as: Meteorin, METRN.

Specificity: Appears to be specific for Meteorin.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Daniels, Peden, Lloyd et al.: "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16." in: Human molecular genetics, Vol. 10, Issue 4, pp. 339-52, 2001 (PubMed).

Nishino, Yamashita, Hashiguchi et al.: "Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension." in: The EMBO journal, Vol. 23, Issue 9, pp. 1998-2008, 2004 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).