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METRN antibody (Meteorin, Glial Cell Differentiation Regulator) (Internal Region)

Details for Product anti-METRN Antibody No. ABIN350460, Supplier: Log in to see
Antigen
  • mtrn
  • zgc:92132
  • wu:fb81a08
  • METRN
  • C16orf23
  • c380A1.2
  • Hyrac
  • RGD1306222
  • 1810034B16Rik
  • meteorin, glial cell differentiation regulator
  • meteorin
  • METRN
  • metrn
  • Metrn
Epitope
Internal Region
10
2
2
1
Reactivity
Human
29
23
17
Host
Rabbit
26
9
1
Clonality
Polyclonal
Conjugate
This METRN antibody is un-conjugated
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
17
13
10
8
5
5
2
2
1
1
Options
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Immunogen A synthetic peptide from the internal region of human Meteorin (METRN) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for Meteorin.
Purification Whole serum
Alternative Name Meteorin (METRN Antibody Abstract)
Background Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
Subcellular location: Secreted Also known as: Meteorin, METRN.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Martin, Han, Gordon, Terry, Prabhakar, She, Xie, Hellsten, Chan, Altherr, Couronne, Aerts, Bajorek, Black, Blumer, Branscomb, Brown, Bruno, Buckingham, Callen, Campbell, Campbell, Campbell, Caoile et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Nishino, Yamashita, Hashiguchi, Fujii, Shimazaki, Hamada: "Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension." in: The EMBO journal, Vol. 23, Issue 9, pp. 1998-2008, 2004 (PubMed).

Daniels, Peden, Lloyd, Horsley, Clark, Tufarelli, Kearney, Buckle, Doggett, Flint, Higgs: "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16." in: Human molecular genetics, Vol. 10, Issue 4, pp. 339-52, 2001 (PubMed).