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MAP2 antibody (MAP-2)

Details for Product anti-MAP-2 Antibody No. ABIN350477, Supplier: Login to see
Antigen
  • p67
  • p67eIF2
  • MAP2A
  • MAP2B
  • MAP2C
  • MAP-2
  • Mtap-2
  • Mtap2
  • MAP2R
  • xmap2
  • MGC53131
  • a730034c02
Reactivity
Rat (Rattus), Mouse (Murine)
240
126
122
58
13
7
6
5
3
2
1
Host
Sheep
188
107
20
2
Clonality
Polyclonal
Conjugate
This MAP2 antibody is un-conjugated
16
15
11
8
8
8
4
3
3
3
3
3
3
3
3
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
211
121
96
58
57
41
38
33
29
22
13
11
4
3
3
1
Supplier
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Immunogen A synthetic peptide from mouse Mtap2 (Microtubule-associated protein 2, MAP-2, MAP 2, MAP2, MAP2R) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for MAP-2.
Purification Whole serum
Alternative Name MAP2
Background Regulates and organizes microtubules, may serve as a scaffolding protein for neuromodulatory activities.
Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Subcellular location: Cytoplasm, cytoskeleton.
Developmental stage: Isoform MAP2C is expressed during embryonic brain development and until postanatal day 10. Isoform MAP2B is expressed throughout brain development. Also known as: Microtubule-associated protein 2, MAP 2, MAP-2, MAP2R.
Research Area Stem Cells, Cytoskeleton
Pathways
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Supplier Images
 image for anti-MAP2 antibody (MAP-2) (ABIN350477) IF on rat brain at 1 : 500 dilution using Sheep antibody to rat, mouse Mtap2 (Microtu...
 image for anti-MAP2 antibody (MAP-2) (ABIN350477) IF on rat brain at 1 : 500 dilution using Sheep antibody to rat, mouse Mtap2 (Microtu...
Background publications Hoffert, Pisitkun, Wang et al.: "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 7159-64, 2006 (PubMed).

Ozer, Halpain: "Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton." in: Molecular biology of the cell, Vol. 11, Issue 10, pp. 3573-87, 2000 (PubMed).

Papandrikopoulou, Doll, Tucker et al.: "Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2." in: Nature, Vol. 340, Issue 6235, pp. 650-2, 1989 (PubMed).

Kindler, Schwanke, Schulz et al.: "Complete cDNA sequence encoding rat high and low molecular weight MAP2." in: Nucleic acids research, Vol. 18, Issue 9, pp. 2822, 1990 (PubMed).

Doll, Papandrikopoulou, Matus: "Nucleotide and amino acid sequences of embryonic rat MAP2c." in: Nucleic acids research, Vol. 18, Issue 2, pp. 361, 1990 (PubMed).

Kindler, Schulz, Goedert et al.: "Molecular structure of microtubule-associated protein 2b and 2c from rat brain." in: The Journal of biological chemistry, Vol. 265, Issue 32, pp. 19679-84, 1991 (PubMed).