Mucolipin 2 (MCOLN2) (internal) antibody

Antigen: Mucolipin 2 (MCOLN2)

Synonyms: TRPML2, TRP-ML2, FLJ36691, C86638, AI549968, 3300002C04Rik, MGC124828, MGC55310, zgc:55310, MGC80330

Epitope: internal

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350485

Additional Information

Alternative name: Mucolipin 2 (Mcoln2, MCLN2,TRPML2) (internal region)

Swiss-Prot: Q8IZK6

Immunogen: A synthetic peptide from c-terminal part of human Mucolipin 2 conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein Also known as: MCLN2,Mucolipin-2, MCOLN2,Mucolipin 2, TRPML2, TRP-ML2, FLJ36691.

Specificity: Appears to be specific for Mucolipin 2.

Application Details

Application Notes: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Di Palma, Belyantseva, Kim et al.: "Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 23, pp. 14994-9, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).