Mucolipin 3 (Mcoln3) antibody

Details for Product No. ABIN350494
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Antigen
Synonyms 6720490O21Rik, TRPML3, Va, TRP-ML3, trp-ml3, trpml3, MCOLN3
Reactivity
Mouse (Murine)
(26), (10), (10), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(26), (2), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(29), (14), (8), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN350494
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Options
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Availability Will be delivered in 7 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from mouse Mucolipin 3 conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for BEX1.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
whole serum
Alternative Name Mucolipin 3
Background SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein (Potential).
Tissue specificity: Expressed in the cochlea, particularly in the inner and outer hair cells. DISEASE: Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. SIMILARITY: Belongs to the transient receptor family, polycystin subfamily. Also known as: Mcoln3Mucolipin 3, Va, TRPML3, MGC124245, MGC124246, 6720490O21Rik.
UniProt Q9R224
Application Notes A dilution of 1: 300 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Di Palma, Belyantseva, Kim et al.: "Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 23, pp. 14994-9, 2002 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Hosts (26), (2), (2), (1)
Reactivities (26), (10), (10), (1), (1), (1), (1), (1), (1)
Applications (29), (14), (8), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (7), (3), (2)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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