ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) antibody

Details for Product No. ABIN350506
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Antigen
Synonyms Atpa-1, BC010319, Nkaa1b, K-ATPase, Na+K+ATPase, atp1a1, atp1a1a.1
Reactivity
Rat (Rattus), Mouse (Murine)
(121), (108), (103), (72), (52), (44), (41), (38), (4), (3), (3), (1), (1), (1)
Host
Rabbit
(122), (18)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(71), (60), (42), (31), (24), (10), (9), (9), (9), (5), (2), (1)
Pubmed 4 references available
Catalog no. ABIN350506
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Options
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from mouse Na+/K+ -ATPase alpha 1 subunit (Sodium/potassium-transporting ATPase alpha-1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for BEX1 and BEX2.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
whole serum
Alternative Name ATP1A1
Background Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Melanosome.
Catalytic activity: ATP + H2O + Na+(In) + K+(Out) = ADP + phosphate + Na+(Out) + K+(In).
Subunit: Composed of three subunits: alpha (catalytic), beta and gamma.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: AT1A1, Sodium/potassium-transporting ATPase subunit alpha-1, Sodium pump subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit, Atp1a1.
UniProt Q9WTZ8
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Vosseller, Hansen, Chalkley et al.: "Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol." in: Proteomics, Vol. 5, Issue 2, pp. 388-98, 2005 (PubMed).

Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).

Wolf-Yadlin, Hautaniemi, Lauffenburger et al.: "Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 14, pp. 5860-5, 2007 (PubMed).

Ballif, Carey, Sunyaev et al.: "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain." in: Journal of proteome research, Vol. 7, Issue 1, pp. 311-8, 2008 (PubMed).

Hosts (122), (18)
Reactivities (121), (108), (103), (72), (52), (44), (41), (38), (4), (3), (3), (1), (1), (1)
Applications (71), (60), (42), (31), (24), (10), (9), (9), (9), (5), (2), (1)
Conjugates (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2)
Epitopes (15), (14), (12), (12), (7), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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