Nedd4 Family Interacting Protein 2 (NDFIP2) (N-Term) antibody

Antigen: Nedd4 Family Interacting Protein 2 (NDFIP2)

Synonyms: N4WBP5A, FLJ25842, KIAA1165, N4wbp5a, mKIAA1165, 0710001O20Rik, 2810436B12Rik, 9130207N19Rik, MGC68708, DKFZp459H0627

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350511

Additional Information

Alternative name: NEDD4 WW domain-binding protein 5A (Ndfip2, NFIP2) (n-terminal)

Swiss-Prot: Q91ZP6

Immunogen: A synthetic peptide from the n-terminal of mouse NEDD4 WW domain-binding protein 5A (Ndfip2, NFIP2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: May be involved in NF-kappa-B and MAPK signaling pathways. May be involved in endocytosis. Regulates ENaC surface expression. SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Ubiquitously expressed, with highest levels in brain, liver, kidney and testis. Also known as: NFIP2, NEDD4 family-interacting protein 2, Ndfip2.

Specificity: Appears to be specific for Ndfip2.

Application Details

Application Notes: IHC, WB. A dilution of 1: 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Konstas, Shearwin-Whyatt, Fotia et al.: "Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29406-16, 2002 (PubMed).

Shearwin-Whyatt, Brown, Wylie et al.: "N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking." in: Journal of cell science, Vol. 117, Issue Pt 16, pp. 3679-89, 2004 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).