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Details for Product No. ABIN350519

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (C-Term) antibody

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Antigen
Synonyms AW490526, GluN2B, NR2B, Nmdar2b, MRD6, NMDAR2B, hNR3, nr2b, nmdar2b
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350519
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of human NMDAR2B (GRIN2B) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in mouse and rat.
Specificity Appears to be specific for NMDAR2B.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Purity whole serum
Alternative Name NMDAR2B (GRIN2B)
Background Function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Subcellular location: Cell membrane, Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane, Multi-pass membrane protein. Also known as: GRIN2B, N-methyl-D-aspartate receptor subunit 3, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDE1, NR2B, NR3.
UniProt Q13224
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Mandich, Schito, Bellone et al.: "Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12." in: Genomics, Vol. 22, Issue 1, pp. 216-8, 1994 (PubMed).

Adams, Foldes, Kamboj: "Human N-methyl-D-aspartate receptor modulatory subunit hNR3: cloning and sequencing of the cDNA and primary structure of the protein." in: Biochimica et biophysica acta, Vol. 1260, Issue 1, pp. 105-8, 1995 (PubMed).

Schito, Pizzuti, Di Maria et al.: "mRNA distribution in adult human brain of GRIN2B, a N-methyl-D-aspartate (NMDA) receptor subunit." in: Neuroscience letters, Vol. 239, Issue 1, pp. 49-53, 1998 (PubMed).

Wu, Dowbenko, Spencer et al.: "Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase." in: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21477-85, 2000 (PubMed).

Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).

Alternatives for antigen "Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B)", type "Antibodies"
Hosts (285), (24), (6)
Reactivities (273), (271), (243), (139), (136), (135), (70), (17), (8), (7), (3), (3), (2), (1)
Applications (184), (90), (90), (90), (41), (38), (36), (20), (19), (10), (4), (4), (1)
Conjugates (9), (9), (9), (9), (9), (9), (9), (9), (9), (9), (9), (6), (6), (6), (6), (6)
Epitopes (39), (34), (32), (23), (23), (23), (19), (17), (9), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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