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NPY antibody (Neuropeptide Y) (AA 20-70)

Details for Product anti-NPY Antibody No. ABIN350525, Supplier: Log in to see
Antigen
  • 0710005A05Rik
  • MGC86288
  • npy
  • NPY
  • NPY02
  • npya
  • npyb
  • prepronpy
  • preproNPY
  • PYY4
  • pyy4
  • RATNPY
  • RATNPY02
  • si:dkey-22m8.5
  • xnpy
Epitope
AA 20-70
20
13
5
5
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Rabbit, Xenopus laevis
141
74
69
14
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Host
Goat
103
52
8
2
1
Clonality
Polyclonal
Conjugate
This NPY antibody is un-conjugated
10
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
92
64
57
53
37
29
14
11
3
3
1
1
1
1
1
1
1
Supplier
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Immunogen A synthetic peptide from aa region 20-70 of mouse NPY (Neuropeptide Y) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including human, rat, zebrafish and xenopus.
Specificity Specific for NPY.
Purification Whole serum
Alternative Name NPY (NPY Antibody Abstract)
Background Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Subcellular location: Secreted
Tissue specificity: One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. Also known as: Neuropeptide Y, Neuropeptide tyrosine, C-flanking peptide of NPY, CPON.
Application Notes A dilution of 1: 300 to 1: 3000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Carninci, Kasukawa, Katayama, Gough, Frith, Maeda, Oyama, Ravasi, Lenhard, Wells, Kodzius, Shimokawa, Bajic, Brenner, Batalov, Forrest, Zavolan, Davis, Wilming, Aidinis, Allen, Ambesi-Impiombato et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Taylor, Wnek, Schroeder, Phillips: "Multiple obesity QTLs identified in an intercross between the NZO (New Zealand obese) and the SM (small) mouse strains." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 2, pp. 95-103, 2001 (PubMed).

Minth, Andrews, Dixon: "Characterization, sequence, and expression of the cloned human neuropeptide Y gene." in: The Journal of biological chemistry, Vol. 261, Issue 26, pp. 11974-9, 1986 (PubMed).

Minth, Bloom, Polak, Dixon: "Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 14, pp. 4577-81, 1984 (PubMed).