G Protein-Coupled Receptor 143 (GPR143) (C-Term) antibody

Antigen: G Protein-Coupled Receptor 143 (GPR143)

Synonyms: OA1, Oa1

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350535

Additional Information

Alternative name: ocular albinism type 1 protein homolog (GPR143, OA1) (c-terminal region)

Swiss-Prot: P70259

Immunogen: A synthetic peptide from mouse ocular albinism type 1 protein homolog (G-protein coupled receptor 143 or GPR143, OA1) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Not known; binds heterotrimeric G proteins. SUBCELLULAR LOCATION: Melanosome membrane; Multi-pass membrane protein. Note: Targeted to intracellular organelles, namely the melanosomes in pigment cells. Also known as: G-protein coupled receptor 143, ocular albinism type 1 protein homolog, MOA1, Gpr143, Oa1.

Specificity: Appears to be specific for GPR143.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Bassi, Incerti, Easty et al.: "Cloning of the murine homolog of the ocular albinism type 1 (OA1) gene: sequence, genomic structure, and expression analysis in pigment cells." in: Genome research, Vol. 6, Issue 9, pp. 880-5, 1997 (PubMed).

Newton, Orlow, Barsh: "Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene." in: Genomics, Vol. 37, Issue 2, pp. 219-25, 1997 (PubMed).