Olfactory Receptor (Olfr412) (C-Term) antibody

Antigen: Olfactory Receptor (Olfr412)

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN350547

Additional Information

Alternative name: olfactory receptor (Olfr412) (c-terminal region)

Swiss-Prot: Q7TRW7

Immunogen: A synthetic peptide as a part of mouse olfactory receptor family 127, subfamily 4 (MOR127-4) conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein Also known as:olfactory receptor Olfr412,olfactory receptor 412, Olfr412.

Specificity: Appears to be specific for MOR127-4P.

Application Details

Application Notes: IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Zhang, Firestein: "The olfactory receptor gene superfamily of the mouse." in: Nature neuroscience, Vol. 5, Issue 2, pp. 124-33, 2002 (PubMed).

Young, Friedman, Williams et al.: "Different evolutionary processes shaped the mouse and human olfactory receptor gene families." in: Human molecular genetics, Vol. 11, Issue 5, pp. 535-46, 2002 (PubMed).

Young, Shykind, Lane et al.: "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels." in: Genome biology, Vol. 4, Issue 11, pp. R71, 2003 (PubMed).