Olfactory Receptor 628 (OLFR628) antibody

Antigen: Olfactory Receptor 628 (OLFR628)

Synonyms: MOR22-1, MOR22-4P, MGC129314, MGC129315, Olfr1526-ps1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350563

Additional Information

Alternative name: olfactory receptor (MOR22-1, Olfr628)

Swiss-Prot: Q9EQQ5

Immunogen: A synthetic peptide as a part of mouse olfactory receptor family 22, subfamily 1 (MOR22-1, Olfr628) conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: Membrane. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html"> The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/">olfactory Receptor Data Base: ORDB <||/a> <||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html">transmembrane Analysis: TM analysis<||/a> Also known as: MOR 3'Beta6,olfactory receptor 628,olfactory receptor Olfr628,olfactory receptor MOR22-1, MGC129314, MGC129315.

Specificity: Appears to be specific for MOR22-1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 400 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Bulger, Bender, van Doorninck et al.: "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 26, pp. 14560-5, 2001 (PubMed).

Zhang, Firestein: "The olfactory receptor gene superfamily of the mouse." in: Nature neuroscience, Vol. 5, Issue 2, pp. 124-33, 2002 (PubMed).

Young, Friedman, Williams et al.: "Different evolutionary processes shaped the mouse and human olfactory receptor gene families." in: Human molecular genetics, Vol. 11, Issue 5, pp. 535-46, 2002 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).