Olfactory Receptor 1C1 (OR1C1) antibody

Antigen: Olfactory Receptor 1C1 (OR1C1)

Synonyms: OR1-42, ORL211, TPCR27, HSTPCR27, OR1.5.10

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350616

Additional Information

Alternative name: olfactory receptor (OR1C1, OR1-42, ORL211, TPCR27)

UniProt: Q15619

Immunogen: A synthetic peptide as a part of human olfactory receptor (OR1C1, OR1-42, ORL211, TPCR27) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. FUNCTION: Odorant receptor SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html" > The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/" >olfactory Receptor Data Base: ORDB <||/a> Also known as:olfactory receptor OR1-42,olfactory receptor, family 1, subfamily C, member 1, OR1C1, OR1-42, ORL211, TPCR27, HSTPCR27.

Specificity: Appears to be specific for Olfactory receptor OR1C1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 200 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Vanderhaeghen, Schurmans, Vassart et al.: "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species." in: Genomics, Vol. 39, Issue 3, pp. 239-46, 1997 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).