Olfactory Receptor, Family 1, Subfamily D, Member 4 (Gene/pseudogene) (OR1D4) antibody

Antigen: Olfactory Receptor, Family 1, Subfamily D, Member 4 (Gene/pseudogene) (OR1D4)

Synonyms: OR17-30, MGC125396, MGC199013

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350617

Additional Information

Alternative name: olfactory receptor (OR1D4, OR17-30 and OR1D5, OR17-31)

Swiss-Prot: P47884

Immunogen: A synthetic peptide as a part of human olfactory receptor (OR1D4, OR17-30 and OR1D5, OR17-31) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. FUNCTION: Odorant receptor SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html"> The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/">olfactory Receptor Data Base: ORDB <||/a> Also known as:olfactory receptor, family 1, subfamily D, member 4 and 5. OR1D4 is also known for OR17-30 and OR1D5 for OR17-31, ORL459..

Specificity: Appears to be specific for Olfactory receptor OR1D4 and OR1D5.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 200 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Glusman, Sosinsky, Ben-Asher et al.: "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster." in: Genomics, Vol. 63, Issue 2, pp. 227-45, 2000 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).