OR1E1, OR1E2 antibody

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Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from human olfactory receptor (OR1E1, OR17-32 and OR1E2, OR17-93) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for Olfactory receptor OR1E1 and OR1E2.
Purification Whole serum
Background Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome.
Function: Odorant receptor
Subcellular location: Cell membrane, Multi-pass membrane protein. Also known as: OR1E1 is also known for:olfactory receptor OR17-18,olfactory receptor-like protein, HGMP07I,olfactory receptor 17-2/17-32, OR17-2, OR17-32,olfactory receptor 13-66, OR13-66,olfactory receptor 5-85, OR5-85, ORL739, ORL589, ORL255. OR1E2 is also known for:olfactory receptor 17-93/17-135/17-136, OR17-93, OR17-135, OR17-136.
Application Notes A dilution of 1 : 200 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Sjöblom, Jones, Wood, Parsons, Lin, Barber, Mandelker, Leary, Ptak, Silliman, Szabo, Buckhaults, Farrell, Meeh, Markowitz, Willis, Dawson, Willson, Gazdar, Hartigan, Wu, Liu, Parmigiani, Park et al.: "The consensus coding sequences of human breast and colorectal cancers. ..." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

Fuchs, Malecova, Linhart, Sharan, Khen, Herwig, Shmulevich, Elkon, Steinfath, OBrien, Radelof, Lehrach, Lancet, Shamir: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Glusman, Sosinsky, Ben-Asher, Avidan, Sonkin, Bahar, Rosenthal, Clifton, Roe, Ferraz, Demaille, Lancet: "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster." in: Genomics, Vol. 63, Issue 2, pp. 227-45, 2000 (PubMed).

Rouquier, Taviaux, Trask, Brand-Arpon, van den Engh, Demaille, Giorgi: "Distribution of olfactory receptor genes in the human genome." in: Nature genetics, Vol. 18, Issue 3, pp. 243-50, 1998 (PubMed).