Olfactory Receptor 1E5 (OR1E1) antibody

Antigen: Olfactory Receptor 1E5 (OR1E1)

Synonyms: OR1E5, OR1E6, HGM071, OR17-2, OR1E8P, OR1E9P, OST547, OR13-66, OR17-32, PTOR1E5

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350618

Additional Information

Alternative name: olfactory receptor (OR1E1, OR17-32 and OR1E2, OR17-93)

UniProt: P30953

Immunogen: A synthetic peptide as a part of human olfactory receptor (OR1E1, OR17-32 and OR1E2, OR17-93) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. FUNCTION: Odorant receptor SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Also known as: OR1E1 is also known for:olfactory receptor OR17-18,olfactory receptor-like protein, HGMP07I,olfactory receptor 17-2/17-32, OR17-2, OR17-32,olfactory receptor 13-66, OR13-66,olfactory receptor 5-85, OR5-85, ORL739, ORL589, ORL255. OR1E2 is also known for:olfactory receptor 17-93/17-135/17-136, OR17-93, OR17-135, OR17-136.

Specificity: Appears to be specific for Olfactory receptor OR1E1 and OR1E2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Rouquier, Taviaux, Trask et al.: "Distribution of olfactory receptor genes in the human genome." in: Nature genetics, Vol. 18, Issue 3, pp. 243-50, 1998 (PubMed).

Glusman, Sosinsky, Ben-Asher et al.: "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster." in: Genomics, Vol. 63, Issue 2, pp. 227-45, 2000 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Sjöblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).