Olfactory Receptor 2A5 (OR2A5) antibody

Antigen: Olfactory Receptor 2A5 (OR2A5)

Synonyms: OR2A8, OR2A26, OR2A11P, OR7-138, OR7-141

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350628

Additional Information

Alternative name: olfactory receptor (OR2A5, OR2A14 and OR2A42)

Swiss-Prot: Q96R48

Immunogen: A synthetic peptide as a part of human olfactory receptor (OR2A5, OR2A14 and OR2A42) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. FUNCTION: Odorant receptor SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html"> The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/">olfactory Receptor Data Base: ORDB <||/a> Also known as:olfactory receptor 2A5,olfactory receptor 7-138/7-141, OR7-138, OR7-141, OR2A26, OR2A8,olfactory receptor 2A14,olfactory receptor OR7-12, OST182, OR2A14P, OR2A6,olfactory receptor 2A42,olfactory receptor OR7-19,olfactory receptor OR7-16, OR2A1.

Specificity: Appears to be specific for olfactory receptors OR2A5, OR2A14 and OR2A42.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 200 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Rouquier, Taviaux, Trask et al.: "Distribution of olfactory receptor genes in the human genome." in: Nature genetics, Vol. 18, Issue 3, pp. 243-50, 1998 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).