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OR2F1 and OR2F2 antibody

Details for Product No. ABIN350633, Supplier: Login to see
Antigen
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from human olfactory receptor (OR2F1 and OR2F2) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for olfactory receptors OR2F1, OR2F2.
Purification Whole serum
Background Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome.
Function: Odorant receptor
Subcellular location: Cell membrane, Multi-pass membrane protein. Also known as: OR2F1, OLF3, OR2F3, OR2F4, OR2F5, OR2F3P, OR14-60, OR7-139, OR7-140,olfactory receptor 2F1,olfactory receptor-like protein OLF3,olfactory receptor, family 2, subfamily F, member 1, OR2F2, OR7-1,olfactory receptor, family 2, subfamily F, member2.
Application Notes A dilution of 1 : 200 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Issel-Tarver, Rine: "The evolution of mammalian olfactory receptor genes." in: Genetics, Vol. 145, Issue 1, pp. 185-95, 1997 (PubMed).