Olfactory Receptor 2F1 (OR2F1) antibody

Antigen: Olfactory Receptor 2F1 (OR2F1)

Synonyms: OLF3, OR2F3, OR2F4, OR2F5, OR2F3P, OR14-60, OR7-139, OR7-140

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350633

Additional Information

Alternative name: olfactory receptor (OR2F1 and OR2F2)

UniProt: Q13607

Immunogen: A synthetic peptide as a part of human olfactory receptor (OR2F1 and OR2F2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. FUNCTION: Odorant receptor SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html" > The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/" >olfactory Receptor Data Base: ORDB <||/a> Also known as: OR2F1, OLF3, OR2F3, OR2F4, OR2F5, OR2F3P, OR14-60, OR7-139, OR7-140,olfactory receptor 2F1,olfactory receptor-like protein OLF3,olfactory receptor, family 2, subfamily F, member 1; OR2F2, OR7-1,olfactory receptor, family 2, subfamily F, member 2.

Specificity: Appears to be specific for olfactory receptors OR2F1, OR2F2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 200 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Issel-Tarver, Rine: "The evolution of mammalian olfactory receptor genes." in: Genetics, Vol. 145, Issue 1, pp. 185-95, 1997 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).