Olfactory Receptor 3A3 (OR3A3) antibody

Antigen: Olfactory Receptor 3A3 (OR3A3)

Synonyms: OR3A6, OR3A7, OR3A8P, OR17-16, OR17-137, OR17-201

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350644

Additional Information

Alternative name: olfactory receptor (OR3A3, OR3A6, OR3A7, OR17-201, OR3A8P, OR17-16, OR17-137)

Swiss-Prot: P47888

Immunogen: A synthetic peptide as a part of human olfactory receptor OR3A3 (OR3A7, OR3A8P, OR3A6, Olfactory receptor 17-201, OR17-201, Olfactory receptor 3A3, OR17-16, OR17-137, OR17-201) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous with the corresponding sequence in Chimpanzee and monkey.

Format: Lyophilized

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein Also known as:olfactory receptor, family 3, subfamily A, member 3; OR3A8P,olfactory receptor 17-201, OR17-201,olfactory receptor 3A3, OR17-16, OR17-137, OR17-201.

Specificity: Appears to be specific for Olfactory receptor OR3A3.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Glusman, Sosinsky, Ben-Asher et al.: "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster." in: Genomics, Vol. 63, Issue 2, pp. 227-45, 2000 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Zody, Garber, Adams et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." in: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006 (PubMed).