Opsin 1 (Cone Pigments), Medium-Wave-Sensitive (OPN1MW) antibody

Antigen: Opsin 1 (Cone Pigments), Medium-Wave-Sensitive (OPN1MW)

Synonyms: CBD, GCP, GOP, CBBM, COD5, OPN1MW1, OPN1MW2, MGC176615, MGC177321, MGC198468, MGC198469, Gcp, OPN1LW, RCP, OPN1MW, RH2-2, grops1, grops2, wu:fk57c11, si:zc263a23.4, RH2-3, si:zc263a23.3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350673

Additional Information

Alternative name: Opn1mw (Opsin 1, green sensitive opsin, M opsin)

UniProt: O35599

Immunogen: A synthetic peptide from mouse Opsin 1 (green-sensitive opsin, M opsin, Opn1mw, Gcp) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.

Format: Lyophilized

Description: FUNCTION: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. May increase spectral sensitivity in dim light. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expresssed in cone photoreceptor cells. Also known as: Green-sensitive opsin, green cone photoreceptor pigment, medium wavelength-sensitive cone opsin, M opsin, Opsin 1, Gcp.

Specificity: Appears to be specific for Opn1mw.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. Expiry date:

Restrictions: For Research Use only

Publications

Sun, Macke, Nathans: "Mechanisms of spectral tuning in the mouse green cone pigment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 16, pp. 8860-5, 1997 (PubMed).

Yokoyama, Radlwimmer: "The "five-sites" rule and the evolution of red and green color vision in mammals." in: Molecular biology and evolution, Vol. 15, Issue 5, pp. 560-7, 1998 (PubMed).

Radlwimmer, Yokoyama: "Genetic analyses of the green visual pigments of rabbit (Oryctolagus cuniculus) and rat (Rattus norvegicus)." in: Gene, Vol. 218, Issue 1-2, pp. 103-9, 1998 (PubMed).

Applebury, Antoch, Baxter et al.: "The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning." in: Neuron, Vol. 27, Issue 3, pp. 513-23, 2000 (PubMed).