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Details for Product No. ABIN350679

Greenred-Sensitive Opsin 1 (OPSG/OPSR) antibody

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Antigen
Synonyms RH2-2, grops1, grops2, wu:fk57c11, si:zc263a23.4, RH2-3, si:zc263a23.3
Reactivity
Human
Host
Rabbit
Clonality Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN350679
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human OPSG and OPSR (green & red-sensitive opsin, OPN1MW, OPN1LW, GCP, RCP, CBBM, opsin 1) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for OPSG and OPSR.
Purity whole serum
Alternative Name OPSG and OPSR (greenred-sensitive opsin opsin 1, M opsin)
Background Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. BIOPHYSICOCHEMICAL PROPERTIES: Absorption:       Abs(max)=530 nm,
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: The three color pigments are found in the cone photoreceptor cells. PTM: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. DISEASE: Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD), also called deuteranopia. Also known as: Green-sensitive opsin, green cone photoreceptor pigment, OPN1MW, OPN1LW, GCP, RCP, CBBM, OPN1MW1, opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan), red-sensitive opsin, red cone photoreceptor pigment, M opsin.
UniProt P04001
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Winderickx, Sanocki, Lindsey et al.: "Defective colour vision associated with a missense mutation in the human green visual pigment gene." in: Nature genetics, Vol. 1, Issue 4, pp. 251-6, 1993 (PubMed).

Nathans, Thomas, Hogness: "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments." in: Science (New York, N.Y.), Vol. 232, Issue 4747, pp. 193-202, 1986 (PubMed).

Applebury, Hargrave: "Molecular biology of the visual pigments." in: Vision research, Vol. 26, Issue 12, pp. 1881-95, 1987 (PubMed).

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